LPS-Hemo – Hemosorbent
Hemosorbent "LPS-hemo" is designed to detoxify the body in septic conditions - especially in the case of endotoxin shock, by selective endotoxin removal of whole blood and plasma.
The sorbent selectively removes sensitinogen nature lipopolysaccharide (endotoxin, LPS) produced and accumulated in the tissues during their invasion predominantly gram-negative microorganisms: escherichia, dysentery, and pseudomonas aeruginosa, sticks typhoid and paratyphoid and some others. Biospecific polymyxin ligand selectively binds LPS, connecting with its lipid portion (lipid A), blocks the active chemical groups, with the LPS structure is dissociated irreversibly.
Hemosorbent "LPS-hemo" has high bio- and hemocompatibility (thromboresistance, no dust particles, low non-specific adsorption of plasma proteins) that provides a good hydrodynamics and kinetics of sorption detoxification.
Hemosorbent for single use in a plastic mass exchange column:
| Title | Value | U measurement | Note |
|---|---|---|---|
| Expiration date | 36 | months | |
| Volume | 55±15* | ml | hemosorbent in individual packing |
| Indicator hydrogen ion concentration, pH | 4-7 | рН | isotonic sodium chloride 0.9% for injection in equilibrium with hemosorbent |
| Sorption capacity | 0.5 | mkg/ml | the specific for LPS |
| Storage conditions | heated storage room | ||
| Type of packaging | column with 70 ml package of welded gas-tight paper and multilayer thermoformable film | |
*Note - there is the possibility of implementing hemosorbent in columns 130.160,310,400,450 ml volume
Сonditions for use:
- Sepsis
- Pyoperitonitis
- Meningitis
- Extensive necrotic soft tissue processes
- Endotoxin shock hypotension
- Pneumonia
- Burn disease, complicated by a bacterial infection
- Urinary tract infections
- Prevention of complications after transplantation of organs and tissues
